Nurse-Led Medication Review May Improve Dementia Care
A pilot study shows reduced medication counts and higher quality of life scores for adults with dementia after 90 days.
Updated on Oct. 15, 2026 in Alzheimer’s

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Should nurse-led medication reviews become a standard practice in nursing homes to improve patient care?
A nurse-led intervention successfully reduced the number of medications prescribed to dementia patients in a small pilot study. After 90 days, participants saw a decrease in total medication use and reported improvements in quality of life scores.
Why it matters
Reducing polypharmacy in dementia patients is crucial, as inappropriate medication use can lead to adverse effects and reduced quality of life. This pilot study suggests that nurse-led coordination may be an effective strategy for optimizing care plans for this vulnerable population.
In a pilot study of 16 dementia patients, researchers recorded a reduction in total medication counts from a median of 13 to 9 after a 90-day intervention. While the findings showed a 10.5-point increase in quality of life scores, a larger study is still needed to confirm these results.
The players
Vanderbilt University
An academic research institution associated with the lead researchers who conducted the study.
The details
Advanced Practice Registered Nurses (APRNs) collaborated with primary prescribers and patient surrogates to systematically review and adjust medication regimens. This process focused on identifying and removing potentially inappropriate medications that were no longer necessary or were causing undue harm. By coordinating directly with the care team, the APRNs ensured that changes were safely implemented and accepted by both the clinicians and the patients' families.
Timeline
September 24-26, 2026: Findings were presented at the ENGAGE26 conference in Orlando, Florida.
90-day follow-up: Researchers recorded the final medication counts and quality of life assessments.
Health Landscape
This research contributes to the broader medical effort to address polypharmacy in patients with dementia. It follows established frameworks like the Beers Criteria, aiming to refine treatment approaches by balancing symptom management against the risks of complex medication regimens.
If you are caring for a loved one with dementia, it may be worth discussing their current medication list with a physician to identify any potential for deprescribing. Ask your doctor if a periodic medication review could help reduce side effects and improve their daily comfort.
The takeaway
Simplifying medication regimens may improve well-being for individuals living with dementia. Keep a current list of all medications, including over-the-counter supplements, to facilitate meaningful conversations with a primary care provider or specialist during your next visit.
Further reading
For more on ongoing research and care strategies, explore our Alzheimer’s section.
Live Poll
Should nurse-led medication reviews become a standard practice in nursing homes to improve patient care?









