Restylane Has Marked 30 Years of Injectable Use
As the brand reaches a three-decade milestone, new designs and clinical approvals expand options for facial volume restoration.
Updated on Oct. 6, 2026 in Beauty
Live Poll
Would you consider using injectable aesthetic treatments to manage signs of aging or weight loss?
Galderma has celebrated 30 years of the Restylane hyaluronic acid injectable brand, which has grown to include 77 million treatments administered globally. The brand is now expanding its focus to address facial volume loss associated with menopause and weight loss medications.
Why it matters
As cosmetic interventions evolve, practitioners are increasingly targeting volume loss related to specific health factors like hormonal changes or medication-driven weight loss. These developments allow for more precise clinical applications to manage facial aesthetic goals.
The brand's safety profile is based on 407,000 patient evaluations across more than 80 clinical trials and 180 scientific publications. Researchers continue to assess the clinical outcomes of these diverse hyaluronic acid formulations.
The players
Galderma
A Switzerland-based pharmaceutical company focused on medical solutions for skin health, including the development of aesthetic injectables.
The details
The Restylane Volyme product utilizes a specialized dual-layer technique, employing both needles and cannulas to address temple hollowing. Additionally, the brand has introduced a redesigned syringe across major international markets to improve ergonomic functionality for clinicians. This new packaging system is fully recyclable and designed to reduce in-clinic waste.
Timeline
March 2026: Restylane Volyme received United States approval for temple correction.
2026: A new syringe design received regulatory approval in the European Union, United States, and Canada.
October 2026: Galderma marked the 30th anniversary of the Restylane brand.
Health Landscape
The Restylane portfolio has achieved certification under the European Union Medical Device Regulation to support its primary technologies. This milestone follows the broader industry move toward more rigorous regulatory documentation for all facial aesthetic devices.
If you are considering aesthetic treatments for volume loss related to menopause or medication-driven weight loss, consult with a board-certified dermatologist or plastic surgeon. Discussing these specific concerns with a qualified provider helps ensure you choose a method appropriate for your skin and anatomy.
The takeaway
Thirty years of clinical data highlights the maturation of injectable hyaluronic acid treatments for facial volume. Always prioritize consultations with licensed medical professionals to understand the safety profile and clinical evidence behind any aesthetic procedure you are considering.
Further reading
For more on the latest developments in aesthetic medicine and skin health, explore our Beauty section.
More information
Find more details on clinical research and brand history at the Galderma official corporate website.
Live Poll
Would you consider using injectable aesthetic treatments to manage signs of aging or weight loss?
