Sioux Falls Now Offers Crohn's Disease Clinical Trials
Patients in South Dakota can now access new treatment research locally without traveling out of state.
Updated on Oct. 30, 2026 in Cancer

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Sanford gastroenterologists in Sioux Falls have launched the first clinical trials for Crohn's disease available in South Dakota. This development provides patients the opportunity to access new potential treatments for the condition locally without needing to travel out of state.
Why it matters
Clinical trials offer a vital avenue for patients seeking treatment options beyond standard care. Local access is particularly significant for South Dakota residents, who previously had to travel long distances to participate in research for this chronic inflammatory bowel disease.
Sanford Health has established the first clinical trial program for Crohn's disease in South Dakota. While trial participants commonly include patients who may have lived with the illness for eight years or more, the specific trial phase and success metrics remain under investigation.
The players
Sanford Health
A major integrated health system in the upper Midwest that provides gastrointestinal care and research opportunities.
The details
Participants in these trials receive direct monitoring by specialist gastroenterologists throughout the duration of the study. The program aims to evaluate potential new treatments, allowing researchers to study their efficacy and safety profile within the body. By participating, patients help generate essential evidence on emerging therapies while remaining under the care of their local clinical team.
Timeline
October 30, 2026: Clinical trials for Crohn's disease were announced in Sioux Falls.
Health Landscape
This expansion follows the pattern set by national research networks to decentralize medical innovation. Bringing trials to regional hubs like Sioux Falls helps bridge the gap between academic research centers and local communities managing chronic digestive diseases.
If you are managing Crohn's disease, consider discussing whether a clinical trial might be a suitable addition to your treatment plan during your next visit with your gastroenterologist. Be sure to ask your doctor about the potential risks and benefits associated with enrolling in an experimental study.
The takeaway
Clinical trials can offer an alternative path for patients who have not found success with current standard-of-care treatments for Crohn's disease. Patients should maintain a dialogue with their physician regarding when and how to consider research participation as part of their long-term care.
Further reading
For broader updates on digestive health and research developments, visit Cancer.
Source note: This article includes information reported by Dakotanewsnow.
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