Glaucoma May Hinder Eye Surgery Recovery Outcomes

Patients with glaucoma saw higher rates of retinal swelling after membrane removal surgery.

Updated on Oct. 26, 2026 in Stroke

Macro photograph of the intricate vascular network and retinal tissue inside a human eye.
A retrospective study from the Wilmer Eye Institute found that glaucoma patients have increased risks of retinal swelling following epiretinal membrane removal surgery. AI Illustration. Upload story photo >

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A retrospective study from the Wilmer Eye Institute reveals that patients with glaucoma may experience poorer visual outcomes after epiretinal membrane removal surgery. Researchers observed higher rates of postoperative swelling in these eyes compared to patients without the condition.

Why it matters

Understanding these potential complications helps patients with glaucoma manage expectations for surgery and discuss the risks of postoperative fluid buildup with their surgeons. Pre-existing retinal conditions may fundamentally alter how the eye responds to membrane removal procedures.

This retrospective study of 156 eyes found that glaucoma patients experienced higher rates of cystic intraretinal fluid and retinoschisis at six months post-surgery than those without the disease. The study evaluated patients who underwent membrane peel surgery between 2010 and 2023.

The players

Wilmer Eye Institute

A prominent ophthalmology department affiliated with Johns Hopkins University that specializes in vision research and care.

The details

The surgery, which removes an epiretinal membrane to improve vision, involves mechanical manipulation of the retinal surface. Researchers propose that in glaucomatous eyes, existing damage to retinal ganglion cells and Müller cells likely reduces the tissue's ability to tolerate the mechanical stress of this procedure. This loss of structural resilience may contribute to increased fluid accumulation and the persistent swelling observed in the scans of glaucoma patients.

Timeline

  1. 2010-2023: Patients underwent membrane peel surgery.

  2. 6 months post-surgery: Researchers observed higher rates of intraretinal fluid and retinoschisis.

  3. 12 months post-surgery: Structural differences persisted between groups.

  4. October 12, 2026: The study was published.

Health Landscape

This research adds to the growing literature on surgical outcomes in patients with pre-existing ocular comorbidities like glaucoma. It highlights a critical need to adjust surgical expectations for patients with underlying retinal vulnerability.

If you have glaucoma and are considering epiretinal membrane removal, ask your ophthalmologist about the specific risks of postoperative macular fluid. Discuss whether your current glaucoma management strategy impacts your candidacy for elective retinal surgery.

The takeaway

While membrane removal is common, the presence of glaucoma may change how your eye heals. Always consult with your retina specialist to review your preoperative OCT scans and discuss your personal risk for postoperative macular swelling.

Further reading

For more information on managing eye health, visit the Stroke section.

Source note: This article includes information reported by Reviewofoptometry.

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Do you trust that your surgeon accounts for all your existing health conditions before operating?