New Male Fertility Test Launched to Assess Sperm Health
The PS Detect test helps identify fertilization competence in men who have normal results from standard semen analysis.
Updated on Oct. 14, 2026 in Men’s Health
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PS Fertility has released the PS Detect diagnostic test, which measures phosphatidylserine levels on sperm to evaluate fertilization capability. The test is designed to provide clarity for men struggling with infertility who previously received normal results from conventional semen analysis.
Why it matters
Standard semen analysis frequently fails to identify male factors, which contribute to approximately 50% of infertility cases. This new test aims to bridge that diagnostic gap by identifying underlying issues in the 20-30% of men who are infertile despite normal conventional test results.
The PS Detect test utilizes a benchmark PS Score of 78% or higher to determine normal sperm fertilization competence. It is intended to be used in conjunction with conventional semen analysis to provide a more comprehensive view of male fertility potential.
The players
PS Fertility
A fertility diagnostics company based in Charlottesville, Virginia, that specializes in developing tools to assess male fertilization competence.
The details
The test works by identifying phosphatidylserine, a biomarker on the surface of live sperm that indicates their ability to fuse with an egg. Clinicians use the resulting PS Score to measure the percentage of sperm expressing this marker, which helps determine if the sperm possess the necessary physiological properties for fertilization. Researchers have observed that PS Scores can improve following varicocele repair surgery, suggesting the test may track changes in sperm quality over time.
Timeline
October 14, 2026: PS Fertility announced the product launch.
Health Landscape
The introduction of this biomarker-based test reflects a move beyond traditional morphology and motility testing in reproductive medicine. It addresses a significant diagnostic gap that has historically left many couples without clear explanations for their infertility.
If you and your partner are facing unexplained infertility, it may be worth discussing whether additional diagnostic testing is appropriate with your physician. This test can provide a more detailed assessment for those who have previously received normal semen analysis results.
The takeaway
Fertility challenges are often multifactorial, and standard tests may not capture the full picture of male reproductive health. If you are concerned about fertility, consult with a reproductive specialist to determine which advanced diagnostic tools are appropriate for your care plan.
Further reading
Learn more about the latest innovations in reproductive care in our Men’s Health section.
More information
For more information on the test's diagnostic capabilities, visit the PS Fertility company website.
Source note: This article includes information reported by Memphis Sun.
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Do you trust that new medical diagnostic tests provide more reliable answers for fertility challenges?
