Fibroid Procedures Both Improved Quality of Life
Two surgical approaches for treating uterine fibroids provided similar long-term relief for patients.
Updated on Sept. 25, 2026 in Women’s Health

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A study comparing laparoscopic radiofrequency ablation and myomectomy found that both procedures led to sustained improvements in symptoms and quality of life over two years. The findings offer insights for patients seeking alternatives to a hysterectomy.
Why it matters
While a hysterectomy is the definitive treatment for uterine fibroids, it is not appropriate for individuals who desire uterine preservation or future fertility. These results confirm that less invasive options can provide lasting relief for those avoiding major surgery.
In a study of 401 participants with a mean age of 39, both laparoscopic radiofrequency ablation and myomectomy resulted in significant quality of life gains over two years. Differences between the two groups remained below clinical significance thresholds for both symptoms and life quality.
The players
Weill Cornell Medicine
An academic medical center that contributes to research in reproductive health and surgery.
The details
Myomectomy involves a surgical procedure to remove the entire fibroid from the uterus. In contrast, laparoscopic radiofrequency ablation targets the center of the fibroid to shrink the tissue over time. Both methods aim to alleviate symptoms while preserving the uterus for individuals who wish to avoid a hysterectomy.
Timeline
2014 was when the study began enrolling participants.
6 months post-procedure, myomectomy patients showed modestly greater symptom improvements.
24 months after the procedures, the between-group differences in symptom improvements disappeared.
Health Landscape
The ULTRA study provides a long-awaited comparative benchmark for evaluating surgical interventions for uterine leiomyomas. This research helps refine the standard of care by demonstrating the durability of non-definitive procedures compared to traditional hysterectomy.
If you are managing uterine fibroids and looking to avoid a hysterectomy, these findings support discussing both ablation and myomectomy with your physician. Consider asking your care team how each procedure aligns with your specific goals for fertility and recovery time.
The takeaway
Both myomectomy and radiofrequency ablation offer effective, uterus-preserving options for long-term symptom relief. Keep track of your specific symptom severity to have an informed conversation with your doctor about which surgical approach may be best for your lifestyle.
Further reading
For more on managing gynecological health, visit Women’s Health.
Source note: This article includes information reported by MedPage Today.
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