Pertussis Cases and Deaths Rise Globally in 2023 Study

A new global study finds that pertussis infections and deaths have increased significantly following the COVID-19 pandemic.

Updated on Oct. 27, 2026 in Diseases — General

Pertussis Cases and Deaths Rise Globally in 2023 Study

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A 2023 study found that an estimated 18.9 million people contracted pertussis, with 115,000 deaths reported globally. While long-term trends show a decline in the disease burden since 1990, infection and mortality rates have risen following the COVID-19 pandemic.

Why it matters

The recent increase in pertussis following the pandemic highlights a shift in global disease trends, particularly among vulnerable infants. Understanding these figures is vital for those monitoring childhood immunization and respiratory health risks on a global scale.

This retrospective study analyzed Global Burden of Disease data across 204 countries and territories to estimate 2023 case and mortality counts. Researchers observed a 66.1% increase in mortality from 2020 to 2023, though overall incidence remains comparable to pre-pandemic 2019 levels.

The details

Pertussis, commonly known as whooping cough, is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. The pathogen colonizes the lining of the throat and lungs, triggering severe coughing fits and potential life-threatening complications, especially in infants. The study indicates that the highest mortality risk is concentrated among infants younger than 6 months, particularly in regions such as sub-Saharan Africa.

Timeline

  1. 1990: The baseline year for comparing long-term pertussis incidence and mortality trends.

  2. 2019: The year used as a benchmark for pre-pandemic incidence levels.

  3. 2020: The baseline year for tracking the post-pandemic increase in cases and deaths.

  4. 2023: The most recent year analyzed for global pertussis burden.

Health Landscape

The findings integrate into the Global Burden of Disease Study to track the multi-decade trajectory of infectious disease control. While historical improvements in vaccination and care have driven long-term declines, the recent rebound underscores the fragility of global immunity post-pandemic.

Parents and caregivers should review vaccination schedules with a pediatrician to ensure infants are protected against pertussis. Because infant mortality remains highest in the first six months of life, early clinical evaluation of persistent, severe coughs is a conversation to have with your doctor.

The takeaway

While global pertussis death rates have dropped significantly since 1990, the recent post-pandemic uptick reinforces the need for consistent immunization. Monitor local public health alerts regarding respiratory outbreaks and maintain regular contact with your primary care provider for recommended immunizations.

Further reading

For more information on respiratory infections, visit our Diseases — General section.

Source note: This article includes information reported by Umn.

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