Maternal RSV Vaccine Rates Remained Low in Studies
Data shows many pregnant people did not receive the RSV vaccine despite its proven ability to protect infants.
Updated on Oct. 12, 2026 in Pregnancy
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A review of over 4 million pregnancies conducted between 2023 and 2025 found that maternal RSV vaccine uptake was significantly lower than expected. The vaccine is designed to reduce the risk of severe infant RSV-related hospitalization by 74 percent.
Why it matters
The RSVpreF vaccine offers a critical shield for newborns during their first months, but low uptake rates leave many infants vulnerable to serious infection. Understanding these trends helps public health officials better support vaccine confidence and access.
This analysis of 16 studies across more than 4 million pregnancies compared vaccination uptake rates from 2023 to 2025. It found a 74 percent reduction in RSV-related infant hospitalizations among those who received the RSVpreF vaccine compared to those who did not.
The details
The RSVpreF vaccine is administered to pregnant individuals between 32 and 36 weeks gestation to trigger the production of protective antibodies. These maternal antibodies cross the placenta to provide passive immunity to the fetus, protecting the infant against severe RSV infection after birth. Current data indicates that individuals who are already up-to-date on other recommended pregnancy immunizations are more likely to accept the RSV vaccine.
Timeline
The RSVpreF vaccine rollout began in 2023.
Data for the review was collected during the 2023-2025 study period.
Health Landscape
The introduction of maternal immunization marks a significant shift in the standard of care for neonatal RSV prevention. This study updates the landscape by quantifying real-world adoption rates following the 2023 RSVpreF vaccine rollout.
If you are pregnant, the RSVpreF vaccine is an important option to discuss with your doctor to help safeguard your infant against severe illness. It is worth asking your provider during prenatal visits about the timing and benefits of the vaccine for your specific pregnancy.
The takeaway
While the RSV vaccine is a powerful tool for preventing severe infant hospitalizations, many pregnant people have yet to receive it. Speak with your healthcare provider about whether this immunization is right for your current pregnancy.
Further reading
Learn more about recommended immunizations during Pregnancy.
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