Injectable Treatment Improved Neck Skin Texture
A new pilot study found that liquid polycaprolactone injections helped increase neck skin firmness over six months.
Updated on Oct. 1, 2026 in Beauty
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Researchers have evaluated the safety and effectiveness of liquid-type polycaprolactone injections for reducing horizontal neck lines in a group of 30 Asian subjects. Participants underwent three treatment sessions to assess changes in skin texture and firmness.
Why it matters
This pilot study explores a potential new approach for addressing skin laxity and textural changes in the neck area. Because the findings are preliminary, further research is needed to establish long-term efficacy and safety for a broader population.
In a pilot study of 30 Asian subjects, researchers tracked skin changes after three sessions of liquid-type polycaprolactone injections. Results showed improved elasticity and reduced distensibility at six months, though these preliminary findings require further confirmation.
The players
Polycaprolactone
A biodegradable synthetic polymer used in clinical injectables to address skin texture and rejuvenation.
The details
The treatment works by using liquid-type polycaprolactone, which is injected into the skin using a subdermal cannula technique. Over the course of three sessions spaced one month apart, the injections aim to improve neck skin quality by altering its physical properties. One participant experienced mild bruising that resolved within eight days, highlighting the need for controlled, blinded follow-up to fully understand the safety profile.
Timeline
Baseline measurements were taken before any injection sessions occurred.
Three injection sessions were administered at one-month intervals.
Follow-up data were collected at one month post-treatment for 29 participants.
Follow-up data were collected at three months post-treatment for 28 participants.
The final assessment of skin parameters and participant satisfaction occurred at six months.
Health Landscape
This study contributes to the clinical evaluation of GOURI-based polycaprolactone treatments in the aesthetic medicine field. It marks a shift toward investigating injectable polymers for non-surgical neck rejuvenation as an alternative to existing skin-tightening modalities.
If you are considering non-surgical neck rejuvenation, it is important to discuss the safety and limitations of new injectable materials with a board-certified dermatologist. Because this was a small pilot study, you should prioritize talking with your doctor about established treatments.
The takeaway
This pilot study suggests that liquid-type polycaprolactone may help improve the texture and firmness of neck skin. If you are concerned about neck skin changes, consult a dermatologist to review which, if any, clinical procedures are appropriate for your specific goals.
Further reading
For more on evolving approaches to dermatological health, visit the Beauty section.
More information
Read the full peer-reviewed research article for details on the study design.
Source note: This article includes information reported by Nature.
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